Genes related to immunity, as expressed in the alfalfa leafcutting bee,  Megachile rotundata , during pathogen challenge | Zendy

Xu J. | Zendy; James R. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Genes related to immunity, as expressed in the alfalfa leafcutting bee, Megachile rotundata , during pathogen challenge

Author(s) -

Xu J.,

James R.

Publication year - 2009

Publication title -

insect molecular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.955

H-Index - 93

eISSN - 1365-2583

pISSN - 0962-1075

DOI - 10.1111/j.1365-2583.2009.00927.x

Subject(s) - biology , gene , honey bee , innate immune system , immune system , pathogen , plant disease resistance , immunity , genetics , microbiology and biotechnology , botany

Virtually nothing is known about disease resistance in solitary bees, so expressed sequence tag (EST) databases were developed to search for immune response genes in the alfalfa leafcutting bee. We identified 104 putative immunity‐related genes from both healthy and pathogen‐challenged bee larvae, and 12 more genes using PCR amplification. The genes identified coded for proteins with a wide variety of innate immune response functions, including pathogen recognition, phagocytosis, the prophenoloxidase cascade, melanization, coagulation and several signalling pathways. Some immune response genes were highly conserved with honey bee genes, and more distantly related to other insects. The data presented provides the first analysis of immune function in a solitary bee and provides a foundation for the further analysis of gene expression patterns in bees.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research