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Cloning and expression analysis of takeout/JHBP family genes of silkworm, Bombyx mori
Author(s) -
Saito K.,
Su Z.H.,
Emi A.,
Mita K.,
Takeda M.,
Fujiwara Y.
Publication year - 2006
Publication title -
insect molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.955
H-Index - 93
eISSN - 1365-2583
pISSN - 0962-1075
DOI - 10.1111/j.1365-2583.2006.00612.x
Subject(s) - bombyx mori , biology , gene , bombyx , complementary dna , gene family , homology (biology) , genetics , cloning (programming) , phylogenetic tree , gene expression , juvenile hormone , insect , botany , computer science , programming language
A Bombyx EST cDNA database was searched using the Drosophila takeout gene and nine cDNAs were obtained. The homology search suggested that these genes are widespread in insects and organize a large gene family, and that they have hydrophobic ligands. A phylogenetic tree indicated that the genes are first divided into two large groups, juvenile hormone binding protein and other protein genes, and the latter group diversified within a short time at an early stage. The expression study of five Bombyx genes indicated that they are expressed in various tissues and are regulated by development and feeding conditions. The Bombyx genes might have roles related to the regulation of metabolism, growth or development related to nutritional conditions.