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Peritrophic matrix proteins of Anopheles gambiae and Aedes aegypti
Author(s) -
Moskalyk L. A.,
Oo M. M.,
JacobsLorena M.
Publication year - 1996
Publication title -
insect molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.955
H-Index - 93
eISSN - 1365-2583
pISSN - 0962-1075
DOI - 10.1111/j.1365-2583.1996.tb00100.x
Subject(s) - aedes aegypti , anopheles gambiae , biology , blood meal , lectin , aedes , biochemistry , larva , dengue fever , virology , zoology , malaria , botany , immunology
Little is known about the composition and function of the mosquito peritrophic matrix (PM), a physical barrier that pathogens must traverse to complete their life cycles. Anopheies gambiae and Aedes aegypti PM proteins induced by blood or by a protein‐free meal have been characterized by the use of 2‐D gel electrophoresis and lectin‐binding affinity assays. More than forty proteins have been identified in both species. Over half of the PM proteins of both mosquitoes migrate identically. Many PM proteins appear to be giycosylated, primarily by high mannose N ‐linked glycosyi groups.