Premium
cDNA structure and characterization of a kinesin‐like protein from the silkworm Bombyx mori
Author(s) -
Okano K.,
Takada N.,
Kobayashi M.,
Maekawa H.
Publication year - 1994
Publication title -
insect molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.955
H-Index - 93
eISSN - 1365-2583
pISSN - 0962-1075
DOI - 10.1111/j.1365-2583.1994.tb00167.x
Subject(s) - biology , bombyx mori , kinesin , complementary dna , aspergillus nidulans , bombyx , schizosaccharomyces pombe , drosophila melanogaster , mitosis , genetics , cdna library , microbiology and biotechnology , microtubule , meiosis , motor protein , gene , saccharomyces cerevisiae , mutant
We have isolated a 1224 bp cDNA clone from a Bombyx mori embryonic cDNA library which contains sequences homologous to the kinesin‐like protein gene, ncd , which is required for distribution of chromosomes at meiosis in Drosophila melanogaster females. This clone includes both a microtubule motor and the ATP‐binding domains found in kinesin‐like proteins. The motor domain is classified in the group of the BimC and cut7 , which have a role in spindle formation during mitosis of Aspergillus nidulans and Schizosaccharomyces pombe , respectively. However, the location of the domain at the carboxy terminus is not common in this family, except for ncd and KAR3.