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The Hsp70 heat‐shock gene family of the mosquito Anopheles albimanus
Author(s) -
Benedict M. Q.,
Cockburn A. F.,
Seawright J. A.
Publication year - 1993
Publication title -
insect molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.955
H-Index - 93
eISSN - 1365-2583
pISSN - 0962-1075
DOI - 10.1111/j.1365-2583.1993.tb00130.x
Subject(s) - anopheles albimanus , biology , gene , genetics , genomic dna , concerted evolution , gene family , gene conversion , dna , anopheles , microbiology and biotechnology , gene duplication , genome , malaria , immunology
Four Hsp70 genes of the malaria vector Anopheles albimanus were isolated from a genomic DNA library as two non‐overlapping clones each containing a pair of divergently transcribed genes having 75% DNA sequence similarity to the protein‐coding regions of the Drosophila metanogaster Hsp70genes. The clones were assigned to two loci on chromosome 2R by in situ hybridization. These clones hybridize strongly to heat‐shock but only weakly to non‐shocked mosquito RNA. The Hsp70 gene family of A. albimanus is undergoing concerted evolution probably by gene conversion. The general arrangement of the genes suggests that divergently transcribed pairs of genes at two loci is an ancient Dipteran arrangement predating the Nematocera/Cyclorrapha divergence.