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A chromatic explosion: the development and future of multiparameter flow cytometry
Author(s) -
Chattopadhyay Pratip K.,
Hogerkorp CarlMagnus,
Roederer Mario
Publication year - 2008
Publication title -
immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.297
H-Index - 133
eISSN - 1365-2567
pISSN - 0019-2805
DOI - 10.1111/j.1365-2567.2008.02989.x
Subject(s) - flow cytometry , computer science , flow (mathematics) , cytometry , biology , data science , immunology , physics , mechanics
Summary Multiparameter flow cytometry has matured tremendously since the 1990s, giving rise to a technology that allows us to study the immune system in unprecedented detail. In this article, we review the development of hardware, reagents, and data analysis tools for multiparameter flow cytometry and discuss future advances in the field. Finally, we highlight new applications that use this technology to reveal previously unappreciated aspects of cell biology and immunity.