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Injection site pseudosarcoma in piriformis syndrome
Author(s) -
Phan Dan C,
Gleason Briana C,
Fan Xuemo,
Chan Owen T M,
Himmelfarb Eric,
Bannykh Serguei I
Publication year - 2011
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.2011.03933.x
Subject(s) - medicine , histopathology , piriformis syndrome , sarcoma , cortisone , surgery , pathology , sciatica
Phan D C, Gleason B C, Fan X, Chan O T M, Himmelfarb E & Bannykh S I
(2011) Histopathology 59 , 327–332 Injection site pseudosarcoma in piriformis syndrome Aims:  Pseudosarcomatous reactive myofibroblastic proliferations have been described following surgery or trauma at a variety of anatomical sites. These types of reactions have not been previously described at injection sites. Here we evaluated prevalence, morphologic patterns and clinical resolution of such lesions. Methods and results:  We analyzed 266 surgical resection specimens obtained during the definitive treatment of piriformis syndrome. Three cases showed exuberant reactive fibroblastic/myofibroblastic intramuscular proliferations, mimicking a sarcoma. In all three cases the surgeries were found to be preceded by local injections of cortisone and bupivacaine. Clinical follow‐up revealed no uncontrolled growth. Conclusions:  As the clinical history of injections is often not provided, it is important to be aware of this pitfall when reviewing skeletal muscle resections for entrapment syndromes.

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