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Hepatocellular prolapse of hepatic portal tracts and subendothelial space of central veins in idiopathic portal hypertension
Author(s) -
SASAKI M.,
NAKANUMA Y.,
WATANABE K.
Publication year - 1995
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1995.tb00293.x
Subject(s) - portal hypertension , medicine , hepatic veins , pathology , hepatocyte , gastroenterology , portal vein , cirrhosis , biology , biochemistry , in vitro
We report a case of idiopathic portal hypertension (IPH) with unusual liver pathology. The liver showed changes similar to these previously reported in IPH and, in addition, we observed the unusual features of prolapse of hepatocytes into portal tracts and also into the subendothelial space of hepatic veins. Hepatocyte prolapse into hepatic veins has previously been reported only in patients with a history of androgenic steroid therapy and immunosuppressive therapy. We speculate that, in our case, prolapse of hepatocytes could be related to the abnormal intrahepatic blood flow or to intrahepatic vasculopathy.