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Lymphoepithelioma‐like carcinoma of the vulvar region
Author(s) -
AXELSEN S.M.,
STAMP I.M.
Publication year - 1995
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1995.tb00222.x
Subject(s) - lymphoepithelioma , lymphoepithelioma like carcinoma , pathology , immunohistochemistry , epstein–barr virus , carcinoma , antigen , virus , medicine , immunology
A case of lymphoepithelioma‐like carcinoma of the vulvar region is described. Histologically, the tumour was similar to lymphoepithelioma of the nasopharynx but was Epstein‐Barr virus negative. Infiltrating lymphocytes were predominantly T‐cells, but also included some B‐cells. Immunohistochemical stains showed positivity in tumour cells for cytokeratins but negativity for neuroendocrine markers, the melanoma‐associated antigen, HMB45 and leucocyte common antigen. We conclude that the tumour histologically resembles lymphoepithelioma of the nasopharynx and lymphoepithelioma‐like carcinomas of the skin, and has no relation to prior infection with the Epstein‐Barr virus.