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Drug‐related pathological lesions of the intestinal tract
Author(s) -
LEE F.D.
Publication year - 1994
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1994.tb01347.x
Subject(s) - pathological , eosinophilia , pathology , medicine , drug , gastrointestinal tract , digestive tract , pharmacology
Pathologists need to be more aware of the capacity of drugs, in particular non‐steroidal anti‐inflammatory agents, to produce a wide spectrum of lesions in the intestinal tract. Whilst the histological changes brought about by drugs are generally non‐specific in character, certain features such as tissue eosinophilia, the presence of apoptotic bodies in the crypts of Leiberkhun or an increase in intra‐epithelial lymphocytes in the colon should always raise the suspicion of drug effects.