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An unusual perilobular pattern of pulmonary interstitial fibrosis associated with Crohn's disease
Author(s) -
DAWSON A.,
GIBBS A.R.,
ANDERSON G.
Publication year - 1993
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1993.tb01242.x
Subject(s) - medicine , pathology , fibrosis , adventitia , crohn's disease , biopsy , parenchyma , disease , pulmonary fibrosis , thickening , chemistry , polymer science
Pulmonary pathology associated with inflammatory bowel disease is rare, and seldom biopsied. In this report, we describe a case of pulmonary interstitial fibrosis associated with Crohn's disease. Biopsy showed a unique pattern, with cellular fibroblastic proliferation and fibrosis affecting interlobular septa, spreading into the parenchymal interstitium from the periphery, with associated lymphoid aggregates and thickening of arterial adventitia.