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Divergent differentiation in small round‐cell tumours of the soft tissues with neural features—an analysis of 10 cases
Author(s) -
PEARSON J.M.,
HARRIS M.,
EYDEN B.P.,
BANERJEE S.S.
Publication year - 1993
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1993.tb01177.x
Subject(s) - immunohistochemistry , pathology , biology , phenotype , soft tissue , cellular differentiation , cell , medicine , gene , genetics
A series of 10 small round‐cell tumours, having in common evidence of neural differentiation, were investigated by immunohistochemistry and electronmicroscopy. In seven, evidence of divergent muscle and/or epithelial differentiation was found. This phenomenon thus appears more common than previously appreciated and suggests that there may be a continuous and overlapping phenotypic spectrum from Ewing's tumour of soft tissue to intra‐abdominal desmoplastic small cell tumour.