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Malignant rhabdoid tumour of the liver. A case report
Author(s) -
FOSCHINI M.P.,
EYKEN P.VAN,
BROCK P.R.,
DAELE M. CASTEELSVAN,
VOS R. DE,
CIN P. DAL,
BERGHE H. VAN DEN,
DESMET V.J.
Publication year - 1992
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1992.tb00946.x
Subject(s) - pathology , medicine
A case of primary malignant rhabdoid tumour of the liver occurring in a 5‐month‐old girl is reported. Histologically the neoplasm presented the ‘typical’ features as described in malignant rhabdoid tumour arising in the kidney. In addition, some areas of the tumour showed a ‘pseudoglandular’ growth pattern. Immunohistochemistry revealed the neoplastic cells to be intensively positive for vimentin and for cytokeratin 19. Variable immunoreactivity for cytokeratin polypeptides 7, 8 and 19 was also detected. On electronmicroscopy the neoplastic cells contained bundles of intermediate filaments, tonofilaments and intercellular junctions. These findings are suggestive of a primitive epithelial differentiation.