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Non‐epithelial cellular components in eccrine spiradenoma: a histological and immunohistochemical study of 20 cases
Author(s) -
ALNAFUSSI A.,
BLESSING K.,
RAHILLY M.
Publication year - 1991
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1991.tb01458.x
Subject(s) - immunohistochemistry , pathology , monoclonal antibody , epithelium , biology , antibody , medicine , immunology
In this study, 20 cases of eccrine spiradenoma have been examined using monoclonal antibodies to identify the nature of the epithelial, as well as the non‐epithelial, cellular components of this tumour. The results indicate that there is striking similarity between the epithelial cells of eccrine spiradenoma and the normal cells lining eccrine apparatus. An interesting finding was the presence of abundant T‐lymphocytes and Langerhans' cells within the tumour lobules. Additionally, endothelial‐lined vascular channels and neurofibrils were prominent in larger lesions.