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Cerebral ganglioglioma with anaplastic oligodendroglial component
Author(s) -
ALLEGRANZA A.,
PILERI S.,
FRANK G.,
FERRACINI R.
Publication year - 1990
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1990.tb00765.x
Subject(s) - ganglioglioma , vimentin , glial fibrillary acidic protein , neurofilament , immunohistochemistry , pathology , monoclonal antibody , biology , medicine , antibody , neuroscience , epilepsy , immunology
We report an unusual and possibly unique example of cerebral ganglioglioma with an anaplastic oligodendroglial component. The latter was documented on both morphological and immunohistochemical grounds. Immunohistochemically, the anaplastic cells were strongly positive with the monoclonal antibody anti‐Leu‐7, while they lacked glial fibrillary acid protein, vimentin and neurofilaments.