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Osteoclast‐like giant cell tumour of the urinary bladder
Author(s) -
AMIR G.,
ROSENMANN E.
Publication year - 1990
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1990.tb00761.x
Subject(s) - giant cell , pathology , osteoclast , urinary bladder , urinary system , acid phosphatase , staining , transitional cell , tartrate resistant acid phosphatase , giant cell tumors , cell , immunohistochemistry , biology , medicine , anatomy , transitional cell carcinoma , receptor , cancer , bladder cancer , enzyme , biochemistry , genetics
We report two cases of osteoclast‐like giant cell tumour of urinary bladder associated with papillary transitional cell tumours. Both cases were morphologically identical to giant cell tumour of bone. The giant cells stained strongly for acid phosphatase which was resistant to tartrate digestion, a staining reaction typical of osteoclasts. In view of the ability of urinary bladder to induce metaplastic and neoplastic bone, we believe that these tumours may represent extraosseous giant cell tumours of bone.