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Lymph node pathology in Henoch‐Schönlein purpura
Author(s) -
Akosa A. B.,
Ali M. H.
Publication year - 1989
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1989.tb03080.x
Subject(s) - medicine , purpura (gastropod) , pathology , lymph , lymph node , henoch schonlein purpura , vasculitis , disease , biology , ecology
This report describes two cases of Henoch‐Schönlein purpura with unusual lymph node pathology. The patients presented with severe colicky abdominal pain mimicking acute appendicitis but a normal appendix was removed in each case. Enlarged mesenteric lymph nodes were removed, with a clinical suspicion of Yersinia infection. Cultures and serology were negative. Histological examination of the lymph nodes revealed follicular granulomas, follicular microabscesses and leucocytoclastic vasculitis. Immunohistochemical studies revealed deposition of IgA, IgG and C 3 in the vessel walls, the finding of IgA supporting a diagnosis of Henoch‐Schönlein purpura.