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An investigation of NCRC11 immunoreactivity in normal and neoplastic epithelia of the female genital tract and ovary
Author(s) -
Hitchcock A.,
Ellis I. O.,
Bell J.,
Robins A.
Publication year - 1989
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1989.tb03066.x
Subject(s) - ovary , female circumcision , monoclonal antibody , pathology , biology , genital tract , immunohistochemistry , antibody , staining , sex organ , mammary gland , carcinoma , cancer , breast cancer , medicine , gynecology , immunology , physiology , endocrinology , genetics
An investigation of NCRC11 immunoreactivity in normal and neoplastic epithelia of the female genital tract and ovary NCRC11 is a monoclonal antibody raised against human mammary carcinoma cells. The prognostic value of tumour cell immunoreactivity to NCRC11 in breast cancer has been shown previously. This study describes NCRC11 immunoreactivity in a wide range of normal and neoplastic epithelial types from the female genital tract and ovary. In the tumours examined, a wide range of staining patterns was seen. The implications of these findings are discussed in relation to the potential uses of this antibody in diagnosis and monitoring of gynaecological diseases.