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Ultrastructure of parathyroid autografts in chronic renal failure including the occurrence of concentric membranous bodies and intermediate filaments
Author(s) -
ELLIS H. A.,
COAKER T.
Publication year - 1989
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1989.tb02168.x
Subject(s) - ultrastructure , chronic renal failure , anatomy , parathyroid gland , medicine , pathology , parathyroid hormone , calcium
The ultrastructure of long‐term parathyroid autografts and their donor glands has been studied in nine patients with chronic renal failure. Autografts showed ultrastructural features of functional activity. Unusual findings included the presence of ‘spironolactone‐like’ concentric membranous bodies derived from the endoplasmic reticulum in one hyperplastic autograft and prominent intracellular intermediate filaments (tonofilaments) in the donor parathyroid gland and recurrent autograft growths in another patient.