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Clear cell rhabdomyosarcoma of the nasal cavity and paranasal sinuses
Author(s) -
CHAN J. K. C.,
NG HK.,
WAN K. Y.,
TSAO S. Y.,
LEUNG T. W. T.,
TSE K. C.
Publication year - 1989
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1989.tb02167.x
Subject(s) - rhabdomyosarcoma , desmin , alveolar rhabdomyosarcoma , nasal cavity , pathology , differential diagnosis , medicine , paranasal sinuses , embryonal rhabdomyosarcoma , immunohistochemistry , sarcoma , anatomy , vimentin
This report describes two cases of alveolar rhabdomyosarcoma of the nasal cavity with unusual histological appearances mimicking clear cell carcinoma. The closely packed tumour cells were polygonal and arranged in sheets and packets. They had an appreciable amount of clear cytoplasm due to accumulation of glycogen. The diagnosis of rhabdomyosarcoma was confirmed by positive staining for desmin and myoglobin. Rhabdomyosarcoma should be included in the differential diagnosis of nasal clear cell tumours, particularly in young adults. A correct diagnosis is important, because chemotherapy is indicated even for apparently localized disease.