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Epstein‐Barr virus (EBV)‐associated undifferentiated carcinoma of the parotid gland
Author(s) -
HUANG D. P.,
NG H. K.,
HO Y. H.,
CHAN K. M.
Publication year - 1988
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1988.tb02075.x
Subject(s) - salivary gland , parotid gland , pathology , virus , epstein–barr virus , biology , immunofluorescence , carcinoma , medicine , antibody , virology , immunology
A case of undifferentiated carcinoma of the salivary gland occurring in the parotid gland of a southern Chinese was reported. Tumour cells showed immunofluorescence for Epstein‐Barr virus (EBV)‐associated nuclear antigen, and DNA hybridization demonstrated the presence of EBV‐DNA in tumour tissue. The findings in this case, together with previous reports, suggest a causal relationship between EBV and salivary gland carcinoma. The relationships between EBV and undifferentiated epithelial tumours of the salivary glands, nasopharynx and thymus are also discussed.