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Liver cell carcinoma with orcein‐positive granules and no identifiable copper
Author(s) -
SHOUSHA S.,
BULL T. B.
Publication year - 1988
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1988.tb02061.x
Subject(s) - orcein , copper , rhodanine , microanalysis , pathology , hepatic carcinoma , carcinoma , chemistry , hepatocellular carcinoma , staining , biology , biochemistry , medicine , cancer research , organic chemistry
A liver cell carcinoma removed surgically by partial hepatectomy from a 79‐year‐old woman contained abundant orcein‐positive granules in many tumour cells. The granules were similar to those usually identified as representing copper‐associated protein, yet they lacked copper, as demonstrated by negative rhodanine and rubeanic acid stains and energy dispersive X‐ray microanalysis.