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Value of long‐core biopsy in the detection of discrete bone marrow lesions
Author(s) -
ISLAM A.,
HENDERSON E. S.
Publication year - 1988
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1988.tb01988.x
Subject(s) - bone marrow , medicine , biopsy , pathology , lesion , core biopsy , peripheral , peripheral blood , myeloid , cancer , breast cancer
A series of 256 bone marrow biopsy specimens was obtained at different times from a group of patients with acute myeloid leukaemia, chronic granulocytic leukaemia and acute lymphoblastic leukaemia, and was analysed in parallel with peripheral blood smears and bone marrow aspirate samples. In five of these biopsy specimens the bone marrow lesion was discrete, deeply seated within the marrow cavity and detected only in long‐core biopsies. Neither peripheral blood nor bone marrow aspirates obtained at the same time established the correct diagnosis. This suggests that when peripheral blood and bone marrow aspirate samples fail to indicate the diagnosis a long‐core biopsy may yield positive results.