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Benign plexiform (multinodular) schwannoma: a rare tumour unassociated with neurofibromatosis
Author(s) -
FLETCHER C.D.M.,
DAVIES S.E.
Publication year - 1986
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1986.tb02595.x
Subject(s) - neurofibromatosis , pathology , schwannoma , dermis , medicine , soft tissue , subcutaneous tissue , pleomorphism (cytology) , immunohistochemistry
In reviewing a large series of soft tissue tumours, seven cases of benign plexiform schwannoma have been retrieved. These were solitary lesions, not associated with von Recklinghausen's neurofibromatosis, which arose in the dermis or subcutaneous tissue, predominantly in young adults. None has recurred. While the schwannomatous nature of these rare lesions is readily appreciated, the frequent presence of nuclear pleomorphism and the plexiform growth pattern should not be regarded as having sinister prognostic significance.