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Histological changes in the genital tract in transsexual women following androgen therapy
Author(s) -
MILLER N.,
BÉDARD Y. C.,
COOTER N. B.,
SHAUL D. L.
Publication year - 1986
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1986.tb02520.x
Subject(s) - transsexual , medicine , androgen , genital tract , sex organ , female circumcision , gynecology , urology , physiology , hormone , psychology , biology , transgender , genetics , psychoanalysis
Thirty‐two young women who desired sexual reassignment were treated with large doses of androgen for a period of 1 year or more, followed by total hysterectomy. Histological examination revealed marked atrophy of cervical epithelium which could mimic dysplasia, and variable degrees of endometrial atrophy. The ovaries showed occasional corpora lutea indicating that even in the face of long term androgen therapy, ovulation may occur.