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Lymph‐node infarction and malignant lymphoma: a multicentre survey of European, English and American cases
Author(s) -
MAURER R.,
SCHMID U.,
DAVIES J.D.,
MAHY N.J.,
STANSFELD A.G.,
LUKES R.J.
Publication year - 1986
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1986.tb02511.x
Subject(s) - medicine , lymphoma , lymph node , lymph , infarction , malignant lymphoma , concomitant , pathology , radiology , myocardial infarction
A multicentre study of 51 cases of lymph‐node infarction seen in the 30‐year period 1956 to 1985 was conducted in order to assess both the short‐ and long‐term prognostic implications of the condition. In 14 cases malignant lymphoma was found synchronously with the infarct. Of the remaining 37 patients with apparently ‘benign’ lymph‐node infarction only six showed manifestations of malignant lymphoma in the follow‐up time studied (x=48 months; range 1‐156 months). These subsequent malignant lymphomas all occurred within 2 years of the lymph‐node infarction. A postal enquiry and collation of other cases in the medical literature indicates that a minority (26 of 81) have developed malignant lymphoma, and that these lymphomas, too, have all appeared within 2 years. Thorough examination of both the infarcted lymph nodes and others resected at the same time is mandatory in order to exclude concomitant or underlying malignant lymphoma. Two years after lymph‐node infarction the risk of malignant lymphoma is negligible.