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Papillary and cystic neoplasm of the pancreas‐an acinar cell tumour?
Author(s) -
LEARMONTH G. M.,
PRICE S. K.,
VISSER A. E.,
EMMS M.
Publication year - 1985
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1985.tb02971.x
Subject(s) - pancreas , immunohistochemistry , pathology , neoplasm , medicine , acinar cell , ultrastructure , intraductal papillary mucinous neoplasm
Two cases of papillary and cystic neoplasm of the pancreas (PCN) occurring in 17 and 21 year old women are reported with ultrastructural and immunohistochemical findings. A review of the English literature shows that although potentially malignant, PCN, which occurs mainly in young women, is amenable to surgical cure. The significance of large PAS positive and alpha‐1‐antitrypsin positive tumour granules; the lack of specificity of alpha‐1‐antitrypsin for pancreatic acinar cells; the possibility of acinar differentiation of PCN; and its separation from pancreaticoblastoma are discussed.