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Dermatofibrosarcoma protuberans: a clinicopathological and immunohistochemical study with a review of the literature
Author(s) -
FLETCHER C. D. M.,
EVANS B. J.,
MACARTNEY J. C.,
SMITH N.,
JONES E. WILSON,
McKEE. P. H.
Publication year - 1985
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1985.tb02878.x
Subject(s) - dermatofibrosarcoma protuberans , immunohistochemistry , pathology , medicine , dermatology , dermatofibrosarcoma , atypical fibroxanthoma
Forty‐one cases of dermatofibrosarcoma protuberans are presented. The clinical features and histopathological appearances are described. Immunohistochemical staining of thirteen cases with antisera to lysozyme, α 1 ‐antichymotrypsin and S‐100 protein has provided no evidence to support either a histiocytic or neuroectodermal origin for these tumours. In reviewing the literature, the histogenetic origin, differential diagnosis and malignant potential of dermatofibrosarcoma protuberans are discussed.