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The immunohistological demonstration of carcinoembryonic antigen in intra‐epithelial and invasive squamous carcinoma of the cervix
Author(s) -
McDICKEN I.W.,
RAINEY MARGARET
Publication year - 1983
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1983.tb02261.x
Subject(s) - carcinoembryonic antigen , pathology , cervix , dysplasia , medicine , carcinoma in situ , squamous metaplasia , epithelium , carcinoma , antigen , cancer , immunology
Using the sensitive peroxidase, anti‐peroxidase immunohistological technique, carcinoembryonic antigen (CEA) was studied in formalin‐fixed, paraffin‐embedded cervical specimens from 225 patients. CEA was demonstrated in 33% of moderate dysplasia, 78.5% of severe dysplasia, 79% of in‐situ carcinoma and 78% of invasive carcinoma. CEA was not demonstrated in normal squamous epithelium, squamous metaplasia, reserve cell hyperplasia nor in mild dysplasia.