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Malignant granular cell tumour (myoblastoma) of the vulva: report of a case and review of the literature
Author(s) -
ROBERTSON A. J.,
McINTOSH W.,
LAMONT P.,
GUTHRIE W.
Publication year - 1981
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1981.tb01768.x
Subject(s) - vulva , carcinoembryonic antigen , immunoperoxidase , pathology , stain , granular cell , neoplasm , lymph , vulvar neoplasm , medicine , staining , antibody , cancer , monoclonal antibody , immunology , central nervous system
A case of malignant granular cell tumour (myoblastoma) which metastasized from the vulva to the regional lymph nodes is presented. Electron microscopy of the metastases demonstrated the presence of numerous intra‐cytoplasmic lysosomes, a feature characteristic of these neoplasms, and the neoplasm was shown to stain strongly for carcinoembryonic antigen (CEA) using the immunoperoxidase technique. Previous reports in the literature of malignant granular cell tumours are reviewed and discussed.