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Mesodermomas: a new embryological approach to primary tumours of coelomic surfaces
Author(s) -
DONNA A.,
BETTA P. G.
Publication year - 1981
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1981.tb01764.x
Subject(s) - mesothelium , mesoderm , coelom , serous fluid , pathology , anatomy , biology , intermediate mesoderm , differential diagnosis , medicine , peritoneum , embryonic stem cell , biochemistry , gene
It appears that the so‐called mesothelium lining the serous cavities is in fact mesoderm, with an epithelial‐like arrangement which persists in the post‐embryological stage. Cellular variability of primary tumours of serous surfaces can be explained on this developmental evidence. The term mesodermoma seems to be justified to define neoplasms arising from undifferentiated and multipotential mesoderm which, in neoplastic disease, exhibits a wide range of differential activity and gives rise to tumours with prevailing myoblastic, angioblastic, lymphoblastic, chondroblastic, osteoblastic, fibroblastic or epithelial‐like features.