Premium
Reticulin impregnation in the diagnosis of malignant melanoma
Author(s) -
BRIGGS J. C.
Publication year - 1980
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1980.tb02945.x
Subject(s) - benignity , pathology , haematoxylin , stain , basement membrane , melanoma , medicine , eosin , staining , malignancy , cancer research
Reticulin patterns were examined in 25 consecutive malignant melanomas, 25 benign cellular naevi and 10 Spitz (benign juvenile) naevi. Absolute features were that a completely intact basement membrane was a strong indicator of benignity and that pericellular reticulin was evidence of subsequent benign behaviour. In routine circumstances, however, the stain was of little diagnostic use, as the borderline cases on haematoxylin and eosin staining were not made any easier to categorize by reticulin stain.