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Cystadenoma of the pancreas: a histological, histochemical and ultrastructural study of seven cases
Author(s) -
BOGOMOLETZ W. V.,
ADNET J. J.,
WIDGREN S.,
STAVROU M.,
McLAUGHLIN J. E.
Publication year - 1980
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1980.tb02924.x
Subject(s) - mucin , ultrastructure , pancreas , cystadenoma , glycogen , cuboidal cell , pathology , mucus , epithelium , biology , columnar cell , exocrine pancreas , electron microscope , medicine , endocrinology , ecology , physics , optics
Seven cases of cystadenoma of the pancreas were examined in detail histologically and histochemically and two variants were identified: a microcyst type lined by glycogen‐rich cuboidal epithelium which also secretes some neutral mucins; and macrocystic type lined exclusively by mucus‐secreting columnar cells which secrete predominantly sulphated acidic mucins with some neutral mucins. Electron microscopy of two cases of the microcystic variant showed neoplastic cells with an ultrastructure comparable to that of centroacinar cells of the normal exocrine pancreas.