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Adenocarcinoma of the pancreas of childhood: a report of two cases
Author(s) -
BENJAMIN E.,
WRIGHT D.H.
Publication year - 1980
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1980.tb02901.x
Subject(s) - histogenesis , pancreas , pathology , adenocarcinoma , ultrastructure , immunohistochemistry , staining , islet , biology , carcinoma , electron microscope , medicine , cancer , endocrinology , insulin , physics , optics
The clinical, gross anatomical, light microscopic and ultrastructural features of two cases of adenocarcinoma of the pancreas of childhood are presented and compared with adult carcinoma of the pancreas. Both tumours showed acinar differentiation and zymogen granules were demonstrated by electron microscopy. A limited immunohistochemical study suggests that staining for α1‐antitrypsin may provide a marker for acinar differentiation. The histogenesis of this tumour is discussed in relation to the possible origins of islet cells.