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Amyloid arthropathy in myelomatosis—intracytoplasmic synovial deposition
Author(s) -
FRENCH B.T.
Publication year - 1980
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1980.tb02894.x
Subject(s) - polyarthritis , amyloidosis , pathology , medicine , amyloid (mycology) , rheumatoid arthritis , arthropathy , arthritis , osteoarthritis , immunology , alternative medicine
An unusual case is described of a West Indian man who presented with symptoms of an acute polyarthritis and who was found to have myelomatosis. At necropsy, generalized amyloidosis was found with particular involvement of synovial tissue. Myelomatosis presenting as an acute polyarthritis resembling rheumatoid arthritis is an uncommon, although well recognized entity, whereas an arthritic picture produced by amyloidosis is exceptional. The occurrence of joint pathology in myelomatosis and amyloidosis is discussed and the unique feature of intracytoplasmic amyloid deposition seen in this case is stressed.