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Eosinophilic gastroenteritis
Author(s) -
JOHNSTONE J. M.,
MORSON B. C.
Publication year - 1978
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1978.tb01726.x
Subject(s) - eosinophilic gastroenteritis , eosinophilia , medicine , submucosa , etiology , eosinophil , asthma , stomach , pathology , gastrointestinal tract , eosinophilic , enteropathy , abdominal pain , allergy , immunology , gastroenterology , disease
Eosinophilic gastroenteritis is an uncommon condition affecting one or more segments of the gastrointestinal tract, mainly the stomach and small bowel, the principal changes being a variable degree of both oedema and eosinophilic infiltration. Occurring at any age it is commonest in the third decade, is often associated with abdominal pain and peripheral blood eosinophilia, and responds to steroids: allergy or asthma occurs in some 25% of patients. The oedema and eosinophilia involve the submucosa generally but any layer of the gut may be affected. The aetiology is discussed: no allergic or other cause has been determined and it is probable that further knowledge of the role of the eosinophil may be necessary before the precise nature of the lesion can be understood. An association of eosinophilic gastroenteritis with malabsorptive or protein‐losing enteropathies is noted.