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A fixation‐decalcification procedure for bone biopsies
Author(s) -
BUSSOLATI G.
Publication year - 1978
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1978.tb01725.x
Subject(s) - bone decalcification , fixation (population genetics) , cancellous bone , bone biopsy , histology , biopsy , chemistry , biomedical engineering , medicine , dentistry , pathology , biochemistry , gene
A procedure for the simultaneous fixation and decalcification of bone biopsies is described. Mild acidic fixatives (such as Bouin's fluid) are effective decalcifying agents when made calcium‐free by a continuous circulation through a column of anion‐binding ion exchange resin. The procedure has been found relatively fast, safe, economic and to provide excellent histology of biopsies containing cancellous bone.