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Methyl‐methacrylate as an embedding medium in histopathology
Author(s) -
VELDE J.,
BURKHARDT R.,
KLEIVERDA KARIN,
LEENHEERSBINNENDIJK LINEKE,
SOMMERFELD WILTRUD
Publication year - 1977
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/j.1365-2559.1977.tb01671.x
Subject(s) - embedding , methyl methacrylate , histopathology , shrinkage , exothermic reaction , polymerization , methacrylate , materials science , process (computing) , computer science , composite material , chemistry , polymer , pathology , organic chemistry , medicine , artificial intelligence , programming language
Methyl‐methacrylate embedding makes it possible to obtain semi‐thin sections rich in detail and without tissue shrinkage. The procedure requires considerable time and labour, and great care must be taken to prevent heat damage to the tissue during the exothermic polymerization process. The original method given by Burkhardt (1966) and later modifications are described and discussed, with special attention to the practical problems encountered and their solutions.