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Optimizing the treatment of haemophilia B: laboratory and clinical perspectives
Author(s) -
ALEDORT L. M.
Publication year - 2010
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1111/j.1365-2516.2010.02298.x
Subject(s) - medicine , haemophilia , factor ix , clotting factor , haemophilia b , pediatrics , blood coagulation factors , haemophilia a , coagulation
Summary. Hemophilia A and B are traditionally thought of as a single bleeding disorder, viewed as opposite sides of the same coin. Yet the differences between the 2 forms of congenital hemophilia extend far beyond the type of deficient clotting factor—factor VIII for hemophilia A and factor IX (FIX) for hemophilia B. This supplement focuses on the unique laboratory and clinical issues associated with FIX replacement therapy for children and adults with hemophilia B.