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Animal models of inhibitors
Author(s) -
REIPERT B.,
ARRUDA V.,
LILLICRAP D.
Publication year - 2010
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1111/j.1365-2516.2010.02293.x
Subject(s) - medicine , clotting factor , animal model , immune system , pathogenesis , immunology , bioinformatics , intensive care medicine , biology
Summary. Antibody responses to clotting factor concentrates remain a major treatment limitation. In conjucation with ongoing clinical studies, the pathogenesis and potential treatment of clotting factor immune responses is being evaluated in a variety of animal models.