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Acquired inhibitor of factor V: first report in China and literature review
Author(s) -
Lu L.,
Liu Y.,
Wei J.,
Zhang L.,
Zhang L.,
Yang R.
Publication year - 2004
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1111/j.1365-2516.2004.01014.x
Subject(s) - medicine , partial thromboplastin time , prothrombin time , factor ix , intensive care medicine , gastroenterology , pediatrics , coagulation
Summary. We reported a 51‐year‐old man who developed a severe haematuria with a prolonged prothrombin time (PT) and activated partial thromboplastin time (aPTT). Laboratory evaluation revealed the presence of specific factor V inhibitors. No underlying diseases and associated conditions have been identified. The patient improved after immunosuppressive therapy. However, the FV level remained low, indicating incomplete inhibitor eradication. The clinical course of our patient was consistent with the observations by others that FV inhibitor can be persistent for months or years.