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Lack of evidence for increased inhibitor incidence in patients switched from plasma‐derived to recombinant factor VIII
Author(s) -
Scharrer I.,
Ehrlich H. J.
Publication year - 2001
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1111/j.1365-2516.2001.00515.x
Subject(s) - medicine , recombinant dna , incidence (geometry) , pharmacology , genetics , gene , biology , physics , optics
De novo inhibitor development is a rare event in PTPs switched from pdFVIII to rFVIII. Based on previously published data of clinical studies a change in FVIII product is unlikely to provoke inhibitor formation.