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A STUDY OF THE POSSIBLE ROLE OF CHELATION IN THE OCCURRENCE OF HYPOMAGNESAEMIA IN SHEEP
Author(s) -
Ashton W. M.,
Sinclair K. B.
Publication year - 1965
Publication title -
grass and forage science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.716
H-Index - 56
eISSN - 1365-2494
pISSN - 0142-5242
DOI - 10.1111/j.1365-2494.1965.tb00406.x
Subject(s) - rumen , chelation , chemistry , ammonium , ammonium carbonate , ammonia , zoology , magnesium , salt (chemistry) , acetic acid , food science , ingestion , nitrogen , biochemistry , nuclear chemistry , inorganic chemistry , organic chemistry , biology , fermentation
Wethers fitted with permanent rumen cannulae were used in a study of the effect of various doses of ammonium salts and E. D.T. A. (ethylene‐diamine‐tetra‐acetic acid, disodium salt) on the pH of rumen digesta and the levels of serum calcium and magnesium. Doses of up to 200 g ammonium acetate had little effect on the pH of rumen contents or on serum Mg levels, but appeared to produce a fall in serum Ca. Ammonium carbonate, however, when given alone or with E. D.T. A., caused a marked increase in the pH of rumen fluid and a temporary fall in the serum Ca level. When given singly, neither ammonium carbonate nor E. D.T. A. significantly affected the levels of serum Mg which were, however, reduced when these compounds were given together, possibly because the increased pH of rumen contents produced by the ammonium carbonate was conducive to chelation of Mg by the E. D.T. A. High levels of ammonia may occur in rumen liquor after the ingestion of young nitrogen‐rich herbage, and it is suggested that chelation of dietary Mg by such compounds as amino acids and peptides, which abound in young herbage, may be a factor concerned in the low ‘availability’ of this form of Mg.