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Preimplantation genetic diagnosis
Author(s) -
Philip Hunter
Publication year - 2005
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.2005.1479_23.x
Subject(s) - citation , information retrieval , computer science , library science , psychology , medicine
Preimplantation genetic diagnosis (PGD) involves testing for specific genetic conditions prior to the implantation [5] of an embryo in the uterine wall. This form of genetic screening has been made possible by the growth of in-vitro fertilization [6] (IVF) technology, which allows for the early stages of development to occur in a laboratory dish rather than in vivo [7]. The purpose of PGD is to identify what are considered to be abnormal embryos in order to select the most desirable embryos for implantation [5]. Diagnosis is comprised of two steps: extraction of one or two cells from an IVF-produced embryo, and application of the PGD test. PGD is important to embryology [8] because it has advanced IVF results and allowed couples more opportunities to deliver a child to term; however, it has also created much controversy.