Premium
Affinity of anti‐GP41 antibody in patients infected with human immunodeficiency virus type I
Author(s) -
RADKOWSKI M.,
LASKUS T.,
GOCH A.,
SLUSARCZYK J.
Publication year - 1993
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1993.tb00790.x
Subject(s) - asymptomatic , antibody , gp41 , human immunodeficiency virus (hiv) , medicine , immune system , immunology , virus , immunopathology , virology , epitope
. Anti‐gp41 antibody affinity was investigated prospectively in 25 patients with asymptomatic and symptomatic HIV‐1 infection for a period of 9–42 months. Major differences in the processs of immune response maturation towards gp41 were observed among individual subjects, however, antibody affinity increased with time in all examined persons including patients with AIDS. Anti‐gp41 affinity values were found to reflect both the duration and the clinical stage of HIV infection