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Sodium lithium counter‐transport is acutely influenced by heparin‐induced extracorporal LDL precipitation
Author(s) -
MESSNER H.,
KLEOPHAS W.,
HEIN D.,
GRIES F. A.,
KÖBBERLING J.
Publication year - 1991
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1991.tb01812.x
Subject(s) - lithium (medication) , medicine , sodium , apheresis , endocrinology , heparin , chemistry , ldl apheresis , platelet , organic chemistry
. Sodium lithium countertransport may be a genetic marker for arterial hypertension and for the risk of diabetic nephropathy in type 1 diabetic patients. Since various factors seem to influence the transport velocity including serum lipid alterations, erythrocytes of seven patients with severe hyperliproteinaemia who were chronically and intermittently treated with LDL apheresis were examined before and immediately after therapy. The LDL apheresis reduced sodium lithium countertransport significantly (0.383 vs 0.269, P <0.02). Therefore, we conclude that serum lipid composition must be considered when interpreting sodium lithium countertransport velocity.