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Severe sodium restriction alone and with potassium supplementation does not alter blood lipoproteins in essential hypertension
Author(s) -
KJELDSEN S. E.,
TAYLOR I.,
WESTHEIM A.,
FOSS O. P.,
LEREN P.,
EIDE I. K.
Publication year - 1987
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1987.tb02398.x
Subject(s) - essential hypertension , medicine , potassium , endocrinology , sodium , blood pressure , cholesterol , urinary system , excretion , chemistry , organic chemistry
. Seventeen 50‐year‐old men, previously untreated and all with mild to moderate essential hypertension, were given a low sodium diet for 2 weeks. During the second week, the diet was supplemented with potassium. Urinary excretion of Na + decreased from 201 ± 11 to 24 ± 5 and 19 ± 4 mmol 24 h −1 , respectively, after 1 and 2 weeks (means ± SE) while the urinary Na + : K + ratio changed from 2:1 to 1:4 and 1:11. Despite significant changes in blood pressure, body weight, serum electrolytes, sympathetic noradrenergic tone, haemoglobin concentration and haematocrit, no significant change appeared in serum total cholesterol, HDL‐cholesterol or triglycerides. Thus, low sodium diet alone and combined with potassium supplementation seems neutral to blood lipoproteins in the treatment of essential hypertension.