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Inhibition of muscular amino acid release by lipid infusion in man
Author(s) -
WICKLMAYR M.,
RETT K.,
SCHWIEGELSHOHN BETTINA,
WOLFRAM G.,
HAILER SUSANNE,
DIETZE G.
Publication year - 1987
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1987.tb02191.x
Subject(s) - amino acid , medicine , chemistry , endocrinology , triglyceride , basal (medicine) , stimulation , proteolysis , fatty acid , insulin , forearm , biochemistry , cholesterol , biology , surgery , enzyme
. Amino acid balances of healthy postabsorptive volunteers were investigated with the forearm technique under the influence of an intravenous infusion of triglyceride emulsions (MCT; LCT/MCT). A decrease of the basal muscular release of most of the amino acids, resulted in an increase of pre‐existant uptake rates. In parallel, arterial concentrations of these amino acids declined. With constant insulin levels and substantially unchanged blood glucose levels, this inhibition of muscular proteolysis and/or stimulation of proteosynthesis is most probably due to the increased level of free fatty acids.