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Haemodynamic effects of prenaterol and cardiac glycosides in patients with recent myocardial infarction
Author(s) -
BOSTRÖM P.Å.,
ANDERSSON J.,
JOHANSSON B. W.,
LILJA B.,
THORELL J.,
TIDFÄLT K.,
WESTERLING S.
Publication year - 1984
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1984.tb01119.x
Subject(s) - ejection fraction , medicine , myocardial infarction , cardiology , decompensation , digitalis , hemodynamics , heart rate , blood pressure , cardiac output , cardiac decompensation , anesthesia , heart failure
. Prenalterol was given to twenty five patients with acute myocardial infarction. Thirteen patients (group B) had signs of cardiac decompensation while twelve (group A) had not. Ejection fraction was determined with 99m Tc‐labelled red blood cells before and after prenalterol (50 μ g kg ‐1 body weight), intravenously. In group B this procedure was repeated after digitalization 2 days later. The ejection fraction increased significantly in group A after prenalterol injection. In group B, prenalterol produced an increase, but this was not significant. After digitalis the ejection fraction increased significantly and prenalterol produced an additional significant rise. No significant changes in blood pressure occurred. Heart rate increased significantly in both groups after prenalterol injection and decreased significantly after digitalis.