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A clinical and immunopathological study of 304 cases of glomerulonephritis in Tunisia
Author(s) -
VERROUST P.,
BENMAIZ H.,
MORELMAROGER L.,
MAHFOUD A.,
GENITEAU M.,
BENAYED H.,
RICHET G.
Publication year - 1979
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1111/j.1365-2362.1979.tb01670.x
Subject(s) - glomerulonephritis , immune system , incidence (geometry) , immunology , acute glomerulonephritis , antibody , medicine , immune complex , pathology , kidney , physics , optics
. 304 cases of glomerulonephritis were biopsied in Tunisia and studied morphologically. The incidence of glomerulonephritis with marked proliferation of endocapillary cells was 60%, a figure considerably higher than in other large series. Using a Clq binding assay, statistically significant levels of immune complexes were found in cases of acute proliferative glomerulonephritis. Amongst other types of glomerulonephritis, circulating immune complexes were frequently found in systemic lupus erythematosus but only in a low percentage of primary glomerulonephritis with or without immunoglobulin deposits.